专利名称：Method for preventing oral disease by
penetrating polymicrobial oral biofilms andkilling oral pathogens
发明人：James L. Ratcliff,David R. Drake,Sally A.
Cunningham,Elena J. Young
申请号：US14589260申请日：20150105公开号：US09682023B2公开日：20170620
摘要：A method for preventing oral diseases caused by dental biofilm and plaqueaccumulation, such as gingivitis and periodontitis by application of a single-phasestabilized chlorine dioxide composition at a concentration range of about 0.005% toabout 0.800% (w/v) at a pH in the range of 6.0 to 7.4. The bactericidal properties ofstabilized chlorine dioxide include reduction (kill) of anaerobic/aerobic/facultative gram-negative and gram-positive oral bacteria occurring in plaque or polymicrobial biofilms.The composition may be in the form of wash, rinse, soak, paste, gel, aerosol spray, orother suitable delivery system.
申请人：James L. Ratcliff,David R. Drake,Sally A. Cunningham,Elena J. Young
地址：Pueblo West CO US,Iowa City IA US,Everett WA US,Maricopa AZ US
国籍：US,US,US,US
代理机构：Von Hellens & Bycer Law
代理人：Matthew L. Bycer
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