专利名称：HIGHLY EFFICIENT PRODUCTION AND
ISOLATION OF VIRAL PARTICLES
发明人：HRINDA, Michael, E.,PRIOR, Christopher,
P.,MITSCHELEN, Jonathan, J.,IRISH, Thomas,W.,WEBER, David, M.,GORE, Richard,S.,HARTER, James, J.,BAY, Pierre, M.,TARR,George, C.
申请号：EP95914170.0申请日：19950322公开号：EP0751988A1公开日：19970108
摘要：This invention is directed to a continuous process for producing viral particlescomprising providing in a perfused growth medium a population of viable virally infectednon-lytic cells, and removing medium containing said cells at a rate to maintain thesteady-state log-phase growth of cells remaining in said perfused growth medium. Theinvention is also directed to a process for purifying retroviral particles comprising passinga solution comprising the retroviral particles and contaminants through an anionexchange resin, and eluting the retroviral particles from the resin.
申请人：THE IMMUNE RESPONSE CORPORATION
地址：5935 Darwin Court Carlsbad, CA 92008 US
国籍：US
代理机构：UEXKÜLL & STOLBERG
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